Gas Chromatography-Mass Spectrometry (GC-MS)

Gas Chromatography-Mass Spectrometry (GC/MS) includes two strong methods to identify substances with low detection limits while also allowing for quantitative analysis. Although GC-MS analyses may be performed on liquid, gaseous, and solid materials, they are generally limited to volatile and semi-volatile chemicals.


Working Principle:

The Gas Chromatography/Mass Spectrometry (GC/MS) device isolates chemical compositions and identifies the constituents at the molecular scale. It is one of the most precise instruments for assessing environmental materials. The GC operates on the premise that when a mixture is heated, it separates into discrete components. The hot gases are passed via a column containing an inert gas. The separated chemicals pour into the MS as they emerge from the column aperture. The mass of the analyte molecule is used to identify chemicals in mass spectrometry.


  • The main benefit of gas chromatography is its high sensitivity & separation capacity, which allows it to separate a wide spectrum of volatile chemicals.
  • It can be upgraded to a mass spectrometer which determines the ion mass-to-charge ratio.
  • It includes several detectors and injectors that may be used for a range of medicines and other purposes.
  • Gas chromatography is substantially quicker than other chromatographic methods in analyzing a material.

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